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Thermo Scientific Chemicals
2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone, 97+%
CAS: 30725-00-9 | C8H12O5 | 188.18 g/mol
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Chemical Identifiers
CAS30725-00-9
IUPAC Name6-(hydroxymethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-one
Molecular FormulaC8H12O5
InChI KeyNHHKFJCWLPPNCN-UHFFFAOYNA-N
SMILESCC1(C)OC2C(CO)OC(=O)C2O1
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Specifications
Specification Sheet
Specification SheetAssay>97.0%
AssaySpecific rotation: -65° to -71°
Assay (unspecified)>97.0%
Assay (unspecified)Specific rotation: -65° to -71°
2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.
Solubility
Soluble in methanol at 50mg/ml, acetone, dichloromethane, ethyl Acetate.
Notes
Soluble in methanol at 50mg/ml
2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.
Solubility
Soluble in methanol at 50mg/ml, acetone, dichloromethane, ethyl Acetate.
Notes
Soluble in methanol at 50mg/ml
RUO – Research Use Only
General References:
- Kotohiro Nomura and Richard R. Schrock.Preparation of Sugar-Coated Homopolymers and Multiblock ROMP Copolymers. Macromolecules.1996, 29, (2), 540-545.
- Amélia P. Rauter; José Figueiredo; Maria Ismael; Tana Canda; Josep Font; Marta Figueredo. Efficient synthesis of α,β-unsaturated γ-lactones linked to sugars. Tetrahedron: Asymmetry.2001, 12, 1131-1146.