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Thermo Scientific Chemicals
6-Aminonicotinamide, 99%
CAS: 329-89-5 | C6H7N3O | 137.14 g/mol
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Chemical Identifiers
CAS329-89-5
IUPAC Name6-aminopyridine-3-carboxamide
Molecular FormulaC6H7N3O
InChI KeyZLWYEPMDOUQDBW-UHFFFAOYSA-N
SMILESNC(=O)C1=CC=C(N)N=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to pale cream or pale yellow
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5%
Assay (HPLC)≥98.5%
Water Content (Karl Fischer Titration)≤0.5%
FormCrystals or powder or crystalline powder
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6-Aminonicotinamide induces apoptosis in tumor cells. It is clinically used in disseminated neoplastic disease. It also acts as 6-phosphogluconate dehydrogenase inhibitor. It aids in the treatment of psoriasis. It is used as cancer chemotherapeutic drug in animals.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in Dimethyl sulfoxide (DMSO). Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are Strong oxidizing agents. Store at -20°C
Soluble in Dimethyl sulfoxide (DMSO). Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are Strong oxidizing agents. Store at -20°C
RUO – Research Use Only
General References:
- Elisabeth Köhler; Hans-Jürgen Barrach; Diether Neubert. Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide analogue of NADP.FEBS Letters.1970,6 225-228.
- H. Herken; K. Lange. Blocking of pentose phosphate pathway in the brain of rats by 6-aminonicotinamide.Naunyn-Schmiedeberg's Archives of Pharmacology.1969,263 496-499.