2-(Trimethylsilylethynyl)pyridine, 97%
2-(Trimethylsilylethynyl)pyridine, 97%
2-(Trimethylsilylethynyl)pyridine, 97%
2-(Trimethylsilylethynyl)pyridine, 97%
Thermo Scientific Chemicals

2-(Trimethylsilylethynyl)pyridine, 97%

CAS: 86521-05-3 | C10H13NSi | 175.306 g/mol
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5 g
Catalog number L11251.03
also known as L11251-03
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Chemical Identifiers
CAS86521-05-3
IUPAC Name2-[2-(trimethylsilyl)ethynyl]pyridine
Molecular FormulaC10H13NSi
InChI KeyWOFPTESETJKCBH-UHFFFAOYSA-N
SMILESC[Si](C)(C)C#CC1=CC=CC=N1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to yellow
FormLiquid or fused solid
Assay (GC)≥96.0%
Refractive Index1.5305-1.5355 @ 20°C
2-(Trimethylsilylethynyl)pyridine is used as a pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-(Trimethylsilylethynyl)pyridine is used as a pharmaceutical intermediate.

Solubility
Insoluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Jesus A. Varela.; Carlos Saa. Construction of Pyridine Rings by Metal-Mediated [2 + 2 + 2] Cycloaddition. Chem. Rev. 2003, 103 (9), 3787-3802.
  2. Mate Erdelyi.; Adolf Gogoll. Rapid Homogeneous-Phase Sonogashira Coupling Reactions Using Controlled Microwave Heating. J. Org. Chem. 2001, 66 (12), 4165-4169.