(S)-(+)-2-Phenylglycinol, 98+%
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(S)-(+)-2-Phenylglycinol, 98+%
(S)-(+)-2-Phenylglycinol, 98+%
(S)-(+)-2-Phenylglycinol, 98+%
Thermo Scientific Chemicals

(S)-(+)-2-Phenylglycinol, 98+%

CAS: 20989-17-7 | C8H11NO | 137.182 g/mol
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Catalog number L13265.14
also known as L13265-14
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Chemical Identifiers
CAS20989-17-7
IUPAC Name(2S)-2-amino-2-phenylethan-1-ol
Molecular FormulaC8H11NO
InChI KeyIJXJGQCXFSSHNL-MRVPVSSYSA-N
SMILESN[C@H](CO)C1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
FormPowder or crystalline powder
Melting Point (clear melt)74-80°C
Solution TestClear (2.5% in 1N HCl)
Assay (Non-aqueous acid-base Titration)≥98.0 to ≤102.0%
Identification (FTIR)Conforms
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(S)-(+)-2-Phenylglycinol is used in the synthesis of chiral, unsymmetrical bisoxazolines. It is used as a reagent for the resolution of acids via the easily hydrolyzed amides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(+)-2-Phenylglycinol is used in the synthesis of chiral, unsymmetrical bisoxazolines. It is used as a reagent for the resolution of acids via the easily hydrolyzed amides.

Solubility
Soluble in chloroform, dimethylsulfoxide and methanol. Limited solubility in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is sensitive to air. Incompatible with oxidizing agents. Store at -20°C.
RUO – Research Use Only

General References:

  1. Pradeep, Chullikkattil P.; Zacharias, Panthapally S.; Das, Samar K. Synthesis and characterization of a chiral dimeric copper(II) complex: Crystal structure of [Cu2(μ-Cl)2(HL)2]· H2O(H2L = S-(-)-2-[(2-hydroxy-1-phenyl-ethylimino)-methyl]-phenol). Journal of Chemical Sciences. 2005, 117 (2), 133-137.
  2. Reagent for the resolution of acids via the easily hydrolyzed amides: J. Org. Chem ., 51, 4836 (1986).