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Thermo Scientific Chemicals
1-Phenyl-2-pyrrolidinone, 99%
CAS: 4641-57-0 | C10H11NO | 161.20 g/mol
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Chemical Identifiers
CAS4641-57-0
IUPAC Name1-phenylpyrrolidin-2-one
Molecular FormulaC10H11NO
InChI KeyJMVIVASFFKKFQK-UHFFFAOYSA-N
SMILESO=C1CCCN1C1=CC=CC=C1
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder or granules or fused solid
Melting Point62-69°C
Appearance (Color)Colorless to white to pale cream or pale yellow or pale pink
Identification (FTIR)Conforms
Assay (GC)≥98.5%
A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
Solubility
Soluble in chloroform and ethyl Acetate. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
Solubility
Soluble in chloroform and ethyl Acetate. Insoluble in water.
Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Mark S Duxbury; Stanley W Ashley; Edward E Whang. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochemical and Biophysical Research Communications.2004, 313(4), 992-997.
- John S Allingham; Robert Smith; & Ivan Rayment. The structural basis of blebbistatin inhibition and specificity for myosin II. Nature Structural & Molecular Biology.2005, 12378 - 379.