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A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Antigen
Serine/threonine kinase
Applications
Kinase Assay
Concentration
0.52mg/mL
Conjugate
Tb (Terbium)/Lanthanide Chelates
Molecular Weight of Antigen
150kDa
Quantity
1 mg
Regulatory Status
RUO, RUO
Research Discipline
Pharma and Biopharma
Primary or Secondary
Primary
Packaging
1 Each
Form
Liquid
Excitation/Emission
340⁄490, 520
Reactivity
Human
Shipping Condition
Dry Ice
Readout
End Point
Reactivity abrv
Hu
Target Gene
Ser/Thr Kinases
Product Line
LanthaScreen™
Contents & Storage
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.
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