Insulin, human recombinant, zinc solution

Gibco Insulin, human recombinant, zinc solution, is a premium product formulated for cell culture applications. Each 5-mL bottle contains human recombinant insulin in solution at a concentration of 4 mg/mL. This product is ideal for supplementing cell culture media to promote cell growth and proliferation across a wide range of mammalian cell types and for studying insulin receptors. The molecular weight of human recombinant insulin is 5807.7 g/mol, and the recommended supplementation range is 2 to 20 μg/mL, depending on the cell type and specific culture requirements.

Key features

• High quality manufacturing—produced in compliance with 21 CFR 820 and ISO 13485 certified facilities, helping ensure reliable quality and consistency
• Animal-free—contains no materials of animal or human origin, helping reduce the risk of contamination
• Sterility tested—each batch is rigorously tested for sterility to help ensure safety and performance

Product benefits

• Enhanced cell growth—insulin is crucial for regulating glucose uptake, protein synthesis, and cell cycle progression, making it an essential supplement for cell culture media
• Wide application—suitable for various mammalian cell types, facilitating diverse research needs

Understanding insulin

Insulin is a peptide hormone secreted by the beta cells of the pancreatic islets. It plays a vital role in regulating carbohydrate, protein, and lipid metabolism by enhancing the membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, triglyceride formation, and the synthesis of proteins and nucleic acids. Insulin is a 51-amino acid polypeptide produced from proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) linked by disulfide bonds. Insulin deficiency leads to diabetes mellitus, a significant health concern globally. Additionally, insulin is involved in the pathology of insulinomas, tumors originating from beta cells.

In cell culture, insulin's role is pivotal due to its influence on critical cellular processes, including glucose uptake, cell cycle regulation, protein synthesis, and cell growth promotion.

Why Choose Gibco insulin?

Gibco Insulin, human recombinant, zinc solution, stands out due to its stringent manufacturing standards, animal-free composition, and sterility testing. It is designed to support high-performance cell culture applications, ensuring reliable and reproducible results.