5-Fluorouracil, 99%

項目搜尋

結構搜尋

Thermo Scientific Chemicals

5-Fluorouracil, 99%

Name: 5-Fluorouracil, 99%
SKU: 228440010

5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution. | CAS: 51-21-8 | C4H3FN2O2 | 130.08 g/mol

變更視圖

Quantity:

1 g

5 g

25 g

Packaging:

Glass bottle

嘗試 chem dex^TM 網路應用程式

產品號碼 228440010

價格 (TWD)

申請報價

Quantity:

1 g

Packaging:

Glass bottle

Request bulk or custom format

化學識別

CAS51-21-8

IUPAC Name5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione

Molecular FormulaC4H3FN2O2

InChI KeyGHASVSINZRGABV-UHFFFAOYSA-N

SMILESFC1=CNC(=O)NC1=O

檢視更多

規格

規格表

Infrared spectrumConforms

Titration with NaOH98.5 to 101.0 % (On dried substance)

Heavy metals (as Pb)=<20 ppm

Sulfated ash=<0.1 %

Loss on drying=<0.5 % (80°C, 4 hrs) (in vacuum)

檢視更多

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid

• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth

Applications

• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression

• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage

RUO – Research Use Only

General References:

Kato, K.; Shah, M.A.; Enzinger, P.; Bennouna, J.; Shen, L.; Adenis, A.; Sun, J.M.; Cho, B.C.; Özgüroğlu, M.; Kojima, T.; Kostorov, V.; Hierro, C.; Zhu, Y.; McLean, L.A.; Shah, S.; Doi, T. KEYNOTE-590: Phase III study of first-line chemotherapy with or without pembrolizumab for advanced esophageal cancer. Future Oncol. 2019, (10), 1057-1066.
Wagner, A.D.; Syn, N.L.; Moehler, M.; Grothe, W.; Yong, W.P.; Tai, B.C.; Ho, J. Unverzagt S. Chemotherapy for advanced gastric cancer. Cochrane Database Syst Rev. 2017, 8(8), CD004064.