These 96-well plates are pre-configured with the most appropriate TaqMan Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment.

The panel of assays in the TaqMan Array 96-well Human Hedgehog Pathway Plate targets genes from the three members of the vertebrate hedgehog (hh) family: Desert hh, Indian hh, and Sonic hh. Also included are two Patched homologs: Ptc1 and Ptc2; and three homologs of Ci (Cubitus interruptus): Gli1, Gli2, and Gli3. Genes from two cell-cell signaling pathways that commonly function in association with Hedgehog signaling (WNT and TGFB) are also included. And other genes involved in signal transduction of the hedgehog signals (MAPK⁄ERK), as well as genes associated with cell differentiation and regulation of development, are included.