Kanamycin sulfate

Kanamycin sulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity. | CAS: 25389-94-0 | C18H38N4O15S | 582.575 g/mol

產品號碼	Quantity
450810500	50 g

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產品號碼 450810500

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CAS25389-94-0

IUPAC Name(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4,5-triol; sulfuric acid

Molecular FormulaC18H38N4O15S

InChI KeyOOYGSFOGFJDDHP-KMCOLRRFSA-N

SMILESOS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

Appearance (Color)White to off-white

Infrared spectrumConforms

Loss on drying=<4.0 %

pH6.5 to 8.5 (1 % in water)

Appearance (Form)Crystalline powder

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Kanamycin sulfate is the sulfate salt form of kanamycin A
It was isolated from Streptomyces kanamyceticus
This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

Kanamycin sulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
This compound is also involved in translating prokaryotic ribosomes
In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

RUO – Research Use Only