Carbenicillin disodium salt, 90%

Name: Carbenicillin disodium salt, 90%
SKU: 455360050

Carbenicillin disodium salt, CAS # 4800-94-6, is the disodium salt form of carbenicillin, a semisynthetic compound with broad-spectrum antibacterial and β-lactamase-resistant activities.

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產品號碼	Quantity
455360050	5 g
455360010	1 g

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產品號碼 455360050

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5 g

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化學識別

CAS4800-94-6

IUPAC Namedisodium (2S,5R,6R)-6-(2-carboxylato-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Molecular FormulaC17H16N2Na2O6S

InChI KeyRTYJTGSCYUUYAL-YCAHSCEMSA-L

SMILES[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)C3=CC=CC=C3)C(=O)N2[C@H]1C([O-])=O

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規格

規格表

Appearance (Color)White to light yellow

Appearance (Form)Powder or crystalline powder

Water=<6.0 %

HPLC>=88 %

Solubility(5 % in water) Clear to light yellow

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Carbenicillin disodium salt is a semisynthetic compound with antibacterial and β-lactamase-resistant activities and is effective against gram-negative bacteria

• In in vitro studies, carbenicillin disodium salt can totally suppress the proliferation of Agrobacterium

Application

• Due to its antibacterial activity this compound can be used to control bacterial cell wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. This can lead to incomplete bacterial cell wall synthesis to eventually cause cell lysis

• It has also been used in studies to evaluate the role of penicillin-sensitive transpeptidases in cell wall biosynthesis

RUO – Research Use Only

Literature References

Cole, M. R.; Hobden, J. A.; Warner, I. M. Recycling Antibiotics into GUMBOS: A New Combination Strategy to Combat Multi-Drug-Resistant Bacteria. Molecules 2015, 20 (4), 6466-6487.

Sonopo, M. S.; Venter, K.; Boyle, G.; Winks, S.; Painter, B. M.; Zeevaart, J. R. Carbon-14 radiolabeling and in vivo biodistribution of a potential anti-TB compound. J. Labelled Comp. Radiopharm. 2015, 58 (2), 23-29.