Ribavirin, 98%

Name: Ribavirin, 98%
SKU: 460480250

Ribavirin, CAS# 36791-04-5, is an antiviral agent and a guanosine analog, which stops viral RNA synthesis and mRNA capping. | CAS: 36791-04-5 | C₈H₁₂N₄O₅ | 244.2 g/mol

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1 g

5 g

25 g

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產品號碼 460480250

價格 (TWD)

Quantity:

25 g

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化學識別

CAS36791-04-5

IUPAC Name1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide

Molecular FormulaC8H12N4O5

InChI KeyIWUCXVSUMQZMFG-AFCXAGJDSA-N

SMILESNC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

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規格

規格表

Infrared spectrumConforms

Appearance (Color)White to off-white

Appearance (Form)Powder

HPLC>=97.5 %

Specific optical rotation-33° to -37° (20°C, 589 nm) (1 % in water)

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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Ribavirin is a broad-spectrum antiviral nucleoside analog
It inhibits viral genome synthesis

Applications

Ribavirin is an antiviral compound
Its metabolite, ribavirin 5'-phosphate, inhibits inosine monophosphate dehydrogenase (IMP), which is involved in GTP biosynthesis

RUO – Research Use Only

General References:

Keppeke, G.D.; et al. IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Div. 2018, 15,13:5.
Li, W.; Shen, F.; Weber, G.; Ribavirin and quercetin synergistically downregulate signal transduction and are cytotoxic in human ovarian carcinoma cells. Oncol Res. 1999, 11(5), 243-7.