2-Chloropyrazine, 98%

Name: 2-Chloropyrazine, 98%
SKU: A10108.14

CAS: 14508-49-7 | C4H3ClN2 | 114.53 g/mol

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Quantity:

5 g

25 g

100 g

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產品號碼 A10108.14

亦稱為 A10108-14

價格 (TWD)

Quantity:

25 g

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化學識別

CAS14508-49-7

規格

規格表

FormLiquid

Appearance (Color)Clear colorless to yellow

Assay (GC)≥97.5%

Water Content (Karl Fischer Titration)≤3%

Refractive Index1.5320-1.5390 @ 20°C

2-Chloropyrazine is used in cardiotonic, in biological, drug, flavoring and perfumery industry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Chloropyrazine is used in cardiotonic, in biological, drug, flavoring and perfumery industry.

Solubility
Soluble in Methanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.

RUO – Research Use Only

General References:

C Gosmini; JY Nédélec; J Périchon. Electrochemical cross-coupling between functionalized aryl halides and 2-chloropyrimidine or 2-chloropyrazine catalyzed by nickel 2, 2'-bipyridine complex. Tetrahedron Letters. 2000, 41, (2), 201-203.
JM Bégouin, C Gosmini. Cobalt-catalyzed cross-coupling between in situ prepared arylzinc halides and 2-chloropyrimidine or 2-chloropyrazine. The Journal of organic chemistry. 2009, 74, (8), 3221-3224.
The activated chlorine is readily displaced by nucleophiles. In an interesting synthesis of a fused pyridine, intramolecular cycloaddition is followed by elimination of HCN via a retro-Diels-Alder reaction: Tetrahedron, 44, 2977 (1988):
Selectively metallated at the 3-position by LDA or Li tetramethylpiperidide. The lithio-derivative reacts with electrophiles in good yield: Synthesis, 881 (1988).