ARP (N-(aminooxyacetyl)-N'-(D-Biotinoyl) hydrazine, Trifluoroacetic Acid Salt)
ARP (<i>N</i>-(aminooxyacetyl)-<i>N</i>'-(D-Biotinoyl) hydrazine, Trifluoroacetic Acid Salt)
Invitrogen™

ARP (N-(aminooxyacetyl)-N'-(D-Biotinoyl) hydrazine, Trifluoroacetic Acid Salt)

ARP (Aldehyde-Reactive Probe) is a biotinylated hydroxylamine that reacts with the exposed aldehyde group formed at abasic sites in damaged深入閱讀
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產品號碼Quantity
A1055010 mg
產品號碼 A10550
價格 (TWD)
10,710.00
온라인 행사
Ends: 31-Dec-2025
15,300.00
您節省 4,590.00 (30%)
Each
新增至購物車
Quantity:
10 mg
價格 (TWD)
10,710.00
온라인 행사
Ends: 31-Dec-2025
15,300.00
您節省 4,590.00 (30%)
Each
新增至購物車
ARP (Aldehyde-Reactive Probe) is a biotinylated hydroxylamine that reacts with the exposed aldehyde group formed at abasic sites in damaged DNA. The biotins bound to the abasic sites can then be quantitated with fluorescent or enzyme-conjugated streptavidin complexes. ARP is suitable for use in microplate assays.
For Research Use Only. Not for use in diagnostic procedures.
規格
Chemical ReactivityCarboxylic Acid, Ketone, Aldehyde
Label or DyeBiotin
Product TypeARP
Quantity10 mg
Reactive MoietyAmine, Hydroxylamine
Shipping ConditionRoom Temperature
Label TypeBiotin and Other Haptens
Unit SizeEach
內容物與存放
Store in freezer (-5 to -30°C).

引用資料與參考文獻 (18)

引用資料與參考文獻
Abstract
Optimizing antibody immobilization strategies for the construction of protein microarrays.
Authors:Peluso P, Wilson DS, Do D, Tran H, Venkatasubbaiah M, Quincy D, Heidecker B, Poindexter K, Tolani N, Phelan M, Witte K, Jung LS, Wagner P, Nock S
Journal:Anal Biochem
PubMed ID:12531195
'Antibody microarrays have the potential to revolutionize protein expression profiling. The intensity of specific signal produced on a feature of such an array is related to the amount of analyte that is captured from the biological mixture by the immobilized antibody (the "capture agent"). This in turn is a function ... More
N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts.
Authors:Atamna H, Paler-Martínez A, Ames BN
Journal:J Biol Chem
PubMed ID:10702229
'Alpha-phenyl-N-t-butyl nitrone (PBN), a spin trap, scavenges hydroxyl radicals, protects tissues from oxidative injury, and delays senescence of both normal human lung fibroblasts (IMR90) and senescence-accelerated mice. N-t-butyl hydroxylamine and benzaldehyde are the breakdown products of PBN. N-t-Butyl hydroxylamine delays senescence of IMR90 cells at concentrations as low as 10 ... More
Detection of abasic sites and oxidative DNA base damage using an ELISA-like assay.
Authors:Kow YW, Dare A
Journal:Methods
PubMed ID:11020331
'Reactive oxygen species produce a wide spectrum of DNA damage, including oxidative base damage and abasic (AP) sites. Many procedures are available for the quantification and detection of base damage and AP sites. However, either these procedures are laborious or the starting materials are difficult to obtain. A biotinylated aldehyde-specific ... More
Direct visualization of abasic sites on a single DNA molecule using fluorescence microscopy.
Authors:Hirose T, Ohtani T, Muramatsu H, Tanaka A
Journal:Photochem Photobiol
PubMed ID:12194206
'A new method was developed to allow direct visualization of damaged sites on individual DNA molecules. Fluorescence in situ hybridization on extended DNA molecules was modified to detect a single abasic site. Abasic sites were specifically labeled with a biotinylated aldehyde-reactive probe and fluorochrome-conjugated streptavidin. The light emitted by a ... More
A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modifications.
Authors:Khidekel N, Arndt S, Lamarre-Vincent N, Lippert A, Poulin-Kerstien KG, Ramakrishnan B, Qasba PK, Hsieh-Wilson LC
Journal:J Am Chem Soc
PubMed ID:14692737