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Thermo Scientific Chemicals
D-(+)-Mannose, 99%
CAS: 3458-28-4 | C6H12O6
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化學識別
CAS3458-28-4
IUPAC Name6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Molecular FormulaC6H12O6
InChI KeyWQZGKKKJIJFFOK-UHFFFAOYNA-N
SMILESOCC1OC(O)C(O)C(O)C1O
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規格
規格表
規格表Identification (FTIR)Conforms
Water Content (Karl Fischer Titration)≤0.5%
Optical Rotation+14.0 ? 0.5? (c = 10 in water)
Appearance (Color)White
FormPowder
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D-mannose acts as an alternative energy source utilized by brain. It is used in the study of assessing the synthesis of amphiphilic glycopolymers and investigating early detection of bronchiolitis obliterans.It may be useful in the treatment of urinary tract infections (UTIs) and carbohydrate-deficient glycoprotein syndrome type 1b. It is also useful in the formation of glycan structure and glycosylation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-mannose acts as an alternative energy source utilized by brain. It is used in the study of assessing the synthesis of amphiphilic glycopolymers and investigating early detection of bronchiolitis obliterans.It may be useful in the treatment of urinary tract infections (UTIs) and carbohydrate-deficient glycoprotein syndrome type 1b. It is also useful in the formation of glycan structure and glycosylation.
Solubility
Soluble in water.
Notes
Hygroscopic. Incompatible with strong oxidizing agents.
D-mannose acts as an alternative energy source utilized by brain. It is used in the study of assessing the synthesis of amphiphilic glycopolymers and investigating early detection of bronchiolitis obliterans.It may be useful in the treatment of urinary tract infections (UTIs) and carbohydrate-deficient glycoprotein syndrome type 1b. It is also useful in the formation of glycan structure and glycosylation.
Solubility
Soluble in water.
Notes
Hygroscopic. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Chiral building block. For use in a 15-step synthesis of the macrocycle (+)-aspicilin, in which 3 of the 4 asymmetric centers come from mannose, see: Helv. Chim. Acta, 72, 1753 (1989).
- Nakagawa, Y.; Watanabe, Y.; Igarashi, Y.; Ito, Y.; Ojika, M. Pradimicin A, a d-mannose-binding antibiotic, binds pyranosides of l-fucose and l-galactose in a calcium-sensitive manner. Bioorg. Med. Chem. Lett. 2015, 25 (15), 2963-2966.
- Zhai, Y.; Dasog, M.; Snitynsky, R. B.; Purkait, T. K.; Aghajamali, M.; Hahn, A. H.; Sturdy, C. B.; Lowary, T. L.; Veinot, J. G. C. Water-soluble photoluminescent D-mannose and L-alanine functionalized silicon nanocrystals and their application to cancer cell imaging. J. Mater. Chem. B 2014, 2 (47), 8427-8433.