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6-Fluoro-2-methylquinoline, 98+%, Thermo Scientific Chemicals
產品號碼: A11469.22
100 g, Each
化學識別
CAS
1128-61-6
IUPAC Name
6-fluoro-2-methylquinoline
Molecular Formula
C10H8FN
InChI Key
GPIARMSVZOEZCV-UHFFFAOYSA-N
SMILES
CC1=CC=C2C=C(F)C=CC2=N1
規格
規格表Appearance (Color)
White to pale cream to pale brown to gray
Form
Crystals or powder or crystalline powder
Assay (GC)
≥98.0%
Identification (FTIR)
Conforms
Melting Point (clear melt)
49.0-55.0?C
說明
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Bronsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
Solubility
Soluble in Chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
Solubility
Soluble in Chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
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