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Thermo Scientific Chemicals
L-Phenylalaninol, 98%
CAS: 3182-95-4 | C9H13NO | 151.21 g/mol
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化學識別
CAS3182-95-4
IUPAC Name(2S)-2-amino-3-phenylpropan-1-ol
Molecular FormulaC9H13NO
InChI KeySTVVMTBJNDTZBF-VIFPVBQESA-N
SMILESN[C@H](CO)CC1=CC=CC=C1
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規格
規格表
規格表Melting Point (clear melt)88.0-94.0°C
Optical Rotation-23.3 to -25.3° (C=5 in ethanol)
Appearance (Color)White to cream to yellow
FormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
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L-Phenylalaninol acts as an antiulcer agent that reduces the secretion of gastric acid and prevents ulcer formation. It inhibits intestinal absorption of L-phenylalanine making it a prospective treatment for phenylketonuria. Further, it reacts with nitriles to form oxazolines, which finds application in palladium-catalyzed allylic substitution. In addition to this, it is also used in amidation for chiral resolution and nicotinamide adenine dinucleotide modeling.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
L-Phenylalaninol acts as an antiulcer agent that reduces the secretion of gastric acid and prevents ulcer formation. It inhibits intestinal absorption of L-phenylalanine making it a prospective treatment for phenylketonuria. Further, it reacts with nitriles to form oxazolines, which finds application in palladium-catalyzed allylic substitution. In addition to this, it is also used in amidation for chiral resolution and nicotinamide adenine dinucleotide modeling.
Solubility
Soluble in chloroform, ethyl acetate, ethanol and methanol.
Notes
Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.
L-Phenylalaninol acts as an antiulcer agent that reduces the secretion of gastric acid and prevents ulcer formation. It inhibits intestinal absorption of L-phenylalanine making it a prospective treatment for phenylketonuria. Further, it reacts with nitriles to form oxazolines, which finds application in palladium-catalyzed allylic substitution. In addition to this, it is also used in amidation for chiral resolution and nicotinamide adenine dinucleotide modeling.
Solubility
Soluble in chloroform, ethyl acetate, ethanol and methanol.
Notes
Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.
RUO – Research Use Only
General References:
- Shi, Z.; Xiao, X.; Mao, D.; Lu, G. Effects of the preparation method on the performance of the Cu/ZnO/Al2O3 catalyst for the manufacture of L-phenylalaninol with high ee selectivity from L-phenylalanine methyl ester. Catal. Sci. Technol. 2014, 4 (4), 1132-1143.
- Liu, X.; Hu, L.; Jiang, L.; Jia, J.; Zhang, D.; Chen, X. Asymmetric Synthesis of Concentricolide. Eur. J. Org. Chem. 2015, 2015 (10), 2291-2296.