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tert-Butyldimethylchlorosilane, 97%, Thermo Scientific Chemicals
產品號碼: A13064.22
100 g, Each
化學識別
CAS
18162-48-6
IUPAC Name
tert-butyl(chloro)dimethylsilane
Molecular Formula
C6H15ClSi
InChI Key
BCNZYOJHNLTNEZ-UHFFFAOYSA-N
SMILES
CC(C)(C)[Si](C)(C)Cl
規格
規格表Melting Point (clear melt)
84.0-94.0°C (non-U.S. specification)
Identification (FTIR)
Conforms (non-U.S. specification)
Appearance (Color)
Colorless to white
Form
Crystals or powder or crystalline powder or lumps or fused solid
Assay (GC)
≥96.0%
說明
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary material for hypolipaemics such as lovastatin and simvastatin. It plays an important role in the preparation of isoxazolines N-oxides from alpha-bromonitroalkanes. It acts as a versatile protecting reagent for amines, amides and alcohols.
Solubility
Soluble in chloroform and ethyl acetate. Insoluble in water.
Notes
Moisture sensitive. Store in cool place. Incompatible with bases, metals, oxidizing agents and alcohols.
RUO – Research Use Only
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