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Thermo Scientific Chemicals
BAPTA, 97%
CAS: 85233-19-8 | C22H24N2O10 | 476.44 g/mol
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化學識別
CAS85233-19-8
IUPAC Name2-{[2-(2-{2-[bis(carboxymethyl)amino]phenoxy}ethoxy)phenyl](carboxymethyl)amino}acetic acid
Molecular FormulaC22H24N2O10
InChI KeyFTEDXVNDVHYDQW-UHFFFAOYSA-N
SMILESOC(=O)CN(CC(O)=O)C1=CC=CC=C1OCCOC1=CC=CC=C1N(CC(O)=O)CC(O)=O
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規格
規格表
規格表Melting Pointca 165-175°C dec. (non-U.S. sourced material)
Appearance (Color)White to pale cream to pale yellow
CommentMaterial sourced in the U.S. and in other countries
Complexometric Titration≥96.0 to ≤104.0% (non-U.S. sourced material)
FormPowder
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Acts as a calcium chelatorBAPTA is used as a selective calcium chelating reagent. It is suitable for the spectrophotometric monitoring of calcium levels. It is a lipophilic diesters of the chelating agent used for the inhibition of proteolytic activities of certain metalloproteinases, calpain and transcatheter arterial chemoembolization (TACE).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Acts as a calcium chelatorBAPTA is used as a selective calcium chelating reagent. It is suitable for the spectrophotometric monitoring of calcium levels. It is a lipophilic diesters of the chelating agent used for the inhibition of proteolytic activities of certain metalloproteinases, calpain and transcatheter arterial chemoembolization (TACE).
Solubility
Soluble in water and sodium bicarbonate.
Notes
Incompatible with oxidizing agents.
Acts as a calcium chelatorBAPTA is used as a selective calcium chelating reagent. It is suitable for the spectrophotometric monitoring of calcium levels. It is a lipophilic diesters of the chelating agent used for the inhibition of proteolytic activities of certain metalloproteinases, calpain and transcatheter arterial chemoembolization (TACE).
Solubility
Soluble in water and sodium bicarbonate.
Notes
Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Matolcsi, M.; Giordano, N. A Novel Explanation for Observed CaMKII Dynamics in Dendritic Spines with Added EGTA or BAPTA. Biophys. J. 2015, 108 (4), 975-985.
- Manno, C.; Ríos, E. A better method to measure total calcium in biological samples yields immediate payoffs. J. Gen. Physiol. 2015, 145 (3), 167-171.