MES monohydrate, 98%
MES monohydrate, 98%
MES monohydrate, 98%
Thermo Scientific Chemicals

MES monohydrate, 98%

CAS: 145224-94-8 | C6H15NO5S | 213.248 g/mol
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產品號碼 A16104.22
亦稱為 A16104-22
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100 g
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化學識別
CAS145224-94-8
IUPAC Name4-(2-sulfonatoethyl)morpholin-4-ium
Molecular FormulaC6H13NO4S
InChI KeySXGZJKUKBWWHRA-UHFFFAOYSA-N
SMILES[O-]S(=O)(=O)CC[NH+]1CCOCC1
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規格Specification Sheet規格表
FormCrystals or powder or crystalline powder
Assay (Aqueous acid-base Titration)≥97.5 to ≤102.5% (as monohydrate)
Identification (FTIR)Conforms
Appearance (Color)White
MES monohydrate is a biological buffer often referred to as Good’s buffer. It is useful for cell culture media and protein based buffer formulations to maintain a stable environment in solution. It is also used in the purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. It is a useful resolving agent for very small proteins on bis-tris gels. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
MES monohydrate is a biological buffer often referred to as Good’s buffer. It is useful for cell culture media and protein based buffer formulations to maintain a stable environment in solution. It is also used in the purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. It is a useful resolving agent for very small proteins on bis-tris gels. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications.

Solubility
Soluble in water.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Biological buffer, pKa = 6.15 at 20°: Biochemistry, 5, 467 (1966).
  2. Rahman, R. N. Z. R. A.; Masomian, M.; Leow, A. T. C.; Ali, M. S. M. Influence of protein solution in nucleation and optimized formulation for the growth of ARM lipase crystal. J. Cryst. Growth 2015, 426, 234-242.
  3. Baumann, P.; Baumgartner, K.; Hubbuch, J. Influence of binding pH and protein solubility on the dynamic binding capacity in hydrophobic interaction chromatography. J. Chromatogr. A 2015, 1396, 77-85.