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Thermo Scientific Chemicals
Evans Blue
CAS: 314-13-6 | C34H24N6Na4O14S4 | 960.79 g/mol
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化學識別
CAS314-13-6
IUPAC Nametetrasodium (6E)-4-amino-6-[2-(4'-{2-[(2E)-8-amino-1-oxo-5,7-disulfonato-1,2-dihydronaphthalen-2-ylidene]hydrazin-1-yl}-3,3'-dimethyl-[1,1'-biphenyl]-4-yl)hydrazin-1-ylidene]-5-oxo-5,6-dihydronaphthalene-1,3-disulfonate
Molecular FormulaC34H24N6Na4O14S4
InChI KeyKBNIFDASRCWYGC-GXNXWABVSA-J
SMILES[Na+].[Na+].[Na+].[Na+].CC1=CC(=CC=C1N\N=C1/C=CC2=C(C=C(C(N)=C2C1=O)S([O-])(=O)=O)S([O-])(=O)=O)C1=CC=C(N\N=C2/C=CC3=C(C=C(C(N)=C3C2=O)S([O-])(=O)=O)S([O-])(=O)=O)C(C)=C1
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規格
規格表
規格表FormPowder and/or Crystals
Specific Absorbance (E 1%/1cm)≥600 (Lambda max in distilled water, pH 7.0)
Appearance (Color)Dark brown to dark red to purple
Assay (Dye)>80%
Color ChangeDark blue to purple on addition of 0.1N NaOH
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Evans Blue is used for estimation of blood volume and in double-labeling procedure for studying axonal branching. It acts as an inhibitor of L-glutamate and kainate receptor-mediated currents. It is also a P2X-selective purinoceptor antagonist. It is also useful in molecular biology.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water.
Notes
Incompatible with strong oxidizing agents.
Soluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Yang, J.; Jiang, Y.; Guo, Y. Measuring Blood-brain-barrier Permeability Using Evans Blue in Mice. Bio-protocol. 2015, 5 (15), 1548.
- Herz, J.; Johnson, K. R.; McGavern, D. B. Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells. J Exp. Med. 2015, 212 (8), 1153-1169.