L-Glutathione, reduced, 97%

Name: L-Glutathione, reduced, 97%
SKU: A18014.06

CAS: 70-18-8 | C10H17N3O6S | 307.321 g/mol

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產品號碼 A18014.06

亦稱為 A18014-06

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5 g

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化學識別

CAS70-18-8

IUPAC Name2-amino-4-({1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid

Molecular FormulaC10H17N3O6S

InChI KeyRWSXRVCMGQZWBV-UHFFFAOYNA-N

SMILESNC(CCC(=O)NC(CS)C(=O)NCC(O)=O)C(O)=O

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規格

規格表

Optical Rotation-17.0 ± 1.5? (C=2 in water)

Appearance (Color)White

FormCrystals or powder or crystalline powder

Assay (Aqueous acid-base Titration)≥96.0 to ≤104.0%

Identification (FTIR)Conforms

L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca²⁺ ions. It is also used in white wine production.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Notes
Store in cool place. Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Calborean, A.; Martin, F.; Marconi, D.; Turcu, R.; Kacso, I. E.; Iarinca, L. B.; Graur, F.; Turcu, I. Adsorption mechanisms of l-Glutathione on Au and controlled nano-patterning through Dip Pen Nanolithography. Mater. Sci. Eng., C 2015, 57, 171-180.
Wang, X.; Chen, X.; Evans, D. G.; Yang, W. A novel biosensor for reduced l-glutathione based on cobalt phthalocyaninetetrasulfonate-intercalated layered double hydroxide modified glassy carbon electrodes. Sens. Actuators, B 2011, 160 (1), 1444-1449.