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Thermo Scientific Chemicals
N-Methylbenzamide, 99%
CAS: 613-93-4 | C8H9NO | 135.17 g/mol
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化學識別
CAS613-93-4
IUPAC NameN-methylbenzamide
Molecular FormulaC8H9NO
InChI KeyNCCHARWOCKOHIH-UHFFFAOYSA-N
SMILESCNC(=O)C1=CC=CC=C1
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規格
規格表
規格表Appearance (Color)White to pale cream
Assay (GC)≥98.5%
Identification (FTIR)Conforms
Melting Point (clear melt)77.0-83.0?C
FormCrystals or powder or crystalline powder
It acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor. It is also employed as a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor. It is also employed as a pharmaceutical intermediate.
Solubility
Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor. It is also employed as a pharmaceutical intermediate.
Solubility
Insoluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- John Paul Kilburn.; Jan Kehler.; Morten Langgård.; Mette N. Erichsen.; Sebastian Leth-Petersen.; Mogens Larsen.; Claus Tornby Christoffersen.; Jacob Nielsen. N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.Bioorg Med Chem.,2010,21(19), 6053-6062.
- Walter H. Puterbaugh.; Charles R. Metalation of N-Methylbenzamide with Excess n-Butyllithium. Condensations with Electrophilic Compounds to Form ortho Derivatives. Cyclizations.J. Org. Chem.,1964,29(4), 853-856.