2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide, 99%
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2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide, 99%
2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide, 99%
2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide, 99%
Thermo Scientific Chemicals

2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide, 99%

CAS: 19805-75-5 | C9H16N2O | 168.24 g/mol
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1 g
5 g
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產品號碼 A18294.03
亦稱為 A18294-03
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化學識別
CAS19805-75-5
IUPAC Name3-carbamoyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-ium
Molecular FormulaC9H17N2O
InChI KeyACFYUJLIWIDSFM-UHFFFAOYSA-O
SMILESCC1(C)[NH2+]C(C)(C)C(=C1)C(N)=O
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規格Specification Sheet規格表
Appearance (Color)White to orange-brown
Assay (Non-aqueous acid-base Titration)≥98.5 to ≤101.5%
Identification (FTIR)Conforms
Assay (HPLC)≥98.5%
Melting Point177.5-183.5?C
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2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide may be used in the synthesis of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide and 3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy free radical.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide may be used in the synthesis of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide and 3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy free radical.

Solubility
Slightly soluble in water.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Ravi A.Shankar; Kalman Hideg; Jay L.Zweier; Periannan Kuppusamy. Targeted antioxidant properties ofN-[(Tetramethyl-3-pyrroline-3-carboxamido) propyl] phthalimide and its nitroxide metabolite in preventing postischemic myocardial injury. JPET. 2000, 292,(3), 838-845.
  2. Karen Wright; Laurence Dutot; Michel Wakselman; Jean-Paul Mazaleyrat, Marco Crisma, Fernando Formaggio, Claudio Toniolo. Synthesis, resolution and assignment of absolute configuration of trans 3-amino-1-oxyl-2,2,5,5-tetramethylpyrrolidine-4-carboxylic acid (POAC), a cyclic, spin-labelled β-amino acid. Tetrahedron. 2008, 64,(19), 4416-4426.