Ethyl methoxyacetate was used as acyl donor during the preparation of enantiomers of several phenylethylamines, as acylation reagent for the aminolysis of 1-phenylethanamine and used in an industrial, lipase-catalyzed kinetic resolution of primary amine.
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Applications
Ethyl methoxyacetate was used as acyl donor during the preparation of enantiomers of several phenylethylamines, as acylation reagent for the aminolysis of 1-phenylethanamine and used in an industrial, lipase-catalyzed kinetic resolution of primary amine.
Solubility
Slightly soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Lourdes Muñoz; Anna M Rodriguez; Gloria Rosell; M Pilar Bosch; Angel Guerrero. Enzymatic enantiomeric resolution of phenylethylamines structurally related to amphetamine. Organic & Biomolecular Chemistry, 2011, 9 (23), 8171-8177.
- Maria Cammenberg; Karl Hult; Seongsoon Park. Molecular basis for the enhanced lipase-catalyzed N-acylation of 1-phenylethanamine with methoxyacetate. ChemBioChem, 2006, 7(11), 1745-1749.