GoPure™ AAVX Affinity Membrane, 1 mL

The GoPure AAVX Affinity Membrane is designed to provide rapid capture of adeno-associated virus (AAV) vectors at small scale. Incorporating CaptureSelect AAVX ligand, the membrane chromatography unit demonstrates broad serotype specificity to both naturally occurring and synthetic AAV capsids.

Features of the GoPure AAVX Affinity Membrane include:

• Up to 5–15 times faster processing time than resin chromatography*
• Broad AAV specificity, including AAV1–AAV8, AAVrh10, and synthetic serotypes
• Binds >1 x 10¹⁴ capsids at 10 second residence time
• High yield of AAV viral vectors directly from cell culture lysates

The GoPure AAVX Affinity Membrane provides efficient, small-scale capture of AAV viral vectors for screening of engineered capsids, as well as analytical sample preparation.

Main characteristics

Membrane bed: proprietary ePTFE composite

Nominal bed volume: 1 mL

Ligand: single-domain [VHH] antibody fragment

Binding capacity: >1 x 10¹⁴ cp/mL at 10 second residence time

Maximum operating pressure: 0.50 MPa (5.0 bar, 72.5 psi)

Formulation buffer: 18% (v/v) ethanol

*Users can typically purify up to 5–15 times faster compared to AAVX Affinity Resin at three-minute residence time.