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Thermo Scientific Chemicals
trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%
CAS: 1197-18-8 | C8H15NO2 | 157.213 g/mol
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化學識別
CAS1197-18-8
IUPAC Name4-(aminomethyl)cyclohexane-1-carboxylic acid
Molecular FormulaC8H15NO2
InChI KeyGYDJEQRTZSCIOI-UHFFFAOYSA-N
SMILESNCC1CCC(CC1)C(O)=O
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規格
規格表
規格表Assay (Non-aqueous acid-base Titration)≥96.0 to ≤104.0%
Appearance (Color)White
FormCrystals or powder or crystalline powder
Identification (FTIR)Conforms
It is an antifibrinolytic agent that is found to inhibit plasmin-induced fibrinolysis. Used in various hemorrhagic diseases , abnormal bleeding in operations. It is also used as a lysine analogue to characterize binding sites in plasminogen.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is an antifibrinolytic agent that is found to inhibit plasmin-induced fibrinolysis. Used in various hemorrhagic diseases , abnormal bleeding in operations. It is also used as a lysine analogue to characterize binding sites in plasminogen.
Solubility
Soluble in water (167 mg/ml), ethanol (<1mg/mL at 25°C). Very slightly soluble in ether, DMSO (<1mg/mL at 25°C), and alcohol.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It is an antifibrinolytic agent that is found to inhibit plasmin-induced fibrinolysis. Used in various hemorrhagic diseases , abnormal bleeding in operations. It is also used as a lysine analogue to characterize binding sites in plasminogen.
Solubility
Soluble in water (167 mg/ml), ethanol (<1mg/mL at 25°C). Very slightly soluble in ether, DMSO (<1mg/mL at 25°C), and alcohol.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- J M Marshall, et al. Conformational studies of human plasminogen and plasminogen fragments: evidence for a novel third conformation of plasminogen.Biochem.,199433 (12), 3599-3606.
- G J Hoover et. al. Amino acids of the recombinant kringle 1 domain of human plasminogen that stabilize its interaction with μ-amino acids.Biochemistry.,199332(41), 10936-10943.