2,2-Bis(hydroxymethyl)-2,2',2″-nitrilotriethanol, 98%
2,2-Bis(hydroxymethyl)-2,2',2″-nitrilotriethanol, 98%
2,2-Bis(hydroxymethyl)-2,2',2″-nitrilotriethanol, 98%
Thermo Scientific Chemicals

2,2-Bis(hydroxymethyl)-2,2',2″-nitrilotriethanol, 98%

CAS: 6976-37-0 | C8H19NO5 | 209.242 g/mol
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產品號碼 B22515.22
亦稱為 B22515-22
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100 g
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化學識別
CAS6976-37-0
IUPAC Name2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
Molecular FormulaC8H19NO5
InChI KeyOWMVSZAMULFTJU-UHFFFAOYSA-N
SMILESOCCN(CCO)C(CO)(CO)CO
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規格Specification Sheet規格表
FormCrystals or powder or crystalline powder
Assay (Non-aqueous acid-base Titration)≥97.5% to ≤102.5%
Identification (FTIR)Conforms
Appearance (Color)White to pale cream

It is used as a biological buffer, organic synthesize, chemical & pharmaceutical intermediate. It is suitable for fractionation of hemoglobin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a biological buffer, organic synthesize, chemical & pharmaceutical intermediate. It is suitable for fractionation of hemoglobin.

Solubility
Soluble in water (209.2 g/L), at 20°C and alcohol.

Notes
Store in cool, dry place in tightly closed containers. Store away from strong oxidizing agents, air.
RUO – Research Use Only

General References:

  1. K H Scheller; T H Abel; P E Polanyi; P K Wenk; B E Fischer; H Sigel. Metal ion/buffer interactions. Stability of binary and ternary complexes containing 2-[bis(2-hydroxyethyl)amino]-2(hydroxymethyl)-1,3-propanediol (Bistris) and adenosine 5'-triphosphate (ATP). European Journal of Biochemistry. 1980, 107 (2), 455-466.
  2. H Kosaka; I Tyuma. Production of superoxide anion by N,N-bis(2-hydroxyethyl)-iminotris(hydroxymethyl)methane buffer during oxidation of oxyhemoglobin by nitrite and effect of inositol hexaphosphate on the oxidation. Biochimica et Biophysica Acta. 1982, 709 (2), 187-193.
  3. Buffer: pH range 5.5 - 8.0.