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Thermo Scientific Chemicals
2-Bromo-5-hydroxypyridine, 95%
CAS: 55717-45-8 | C5H6BNO | 106.92 g/mol
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化學識別
CAS55717-45-8
IUPAC Name6-boranylpyridin-3-ol
Molecular FormulaC5H6BNO
InChI KeyADHMWMAEKRZWPB-UHFFFAOYSA-N
SMILESBC1=CC=C(O)C=N1
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規格
規格表
規格表Appearance (Color)White to cream to pale brown or pale pink
Melting Point (clear melt)130.0-142.0?C
FormPowder
Assay (GC)≥94.0%
It is used as an active pharmaceutical intermediate and in the coupling reactions with halo aromatic amines and alcohols for a practical synthetic route to 2-substituted amino phenyl and hydroxyphenyl pyridines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used as an active pharmaceutical intermediate and in the coupling reactions with halo aromatic amines and alcohols for a practical synthetic route to 2-substituted amino phenyl and hydroxyphenyl pyridines.
Solubility
Slightly soluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
It is used as an active pharmaceutical intermediate and in the coupling reactions with halo aromatic amines and alcohols for a practical synthetic route to 2-substituted amino phenyl and hydroxyphenyl pyridines.
Solubility
Slightly soluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Yulin Wu, et al. 2,5-Disubstituted pyridines as potent GPR119 agonists.Bioorg. Med. Chem. Lett.,2010,20(8), 2577-2581.
- Seung-Hoi Kim, et al. Coupling reactions with haloaromatic amines and alcohols for a practical synthetic route to 2-substituted aminophenyl and hydroxyphenyl pyridines.Tetrahedron Lett.,2009,50(31), 3242-46.