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Thermo Scientific Chemicals
3-Maleimidopropionic acid N-hydroxysuccinimide ester, 99%
CAS: 55750-62-4 | C11H10N2O6 | 266.209 g/mol
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化學識別
CAS55750-62-4
IUPAC Name2,5-dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
Molecular FormulaC11H10N2O6
InChI KeyJKHVDAUOODACDU-UHFFFAOYSA-N
SMILESO=C(CCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O
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規格
規格表
規格表Assay (unspecified)≥98.5 to ≤101.5% based on Carbon and Nitrogen EA
Elemental AnalysisCarbon C: 48.89-50.37% (theory 49.63%)
Elemental AnalysisNitrogen N: 10.37-10.68% (theory 10.52%)
Identification (FTIR)Conforms
Melting Point (clear melt)161-170?C
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3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat, water, moisture.
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat, water, moisture.
RUO – Research Use Only
General References:
- Kleanthis G. Dendrinos,; Aristotle G. Kalivretenos. Synthesis of N-hydroxysuccinimide esters using polymer bound HOBT. Tetrahedron Letters. 1998, 39(11), 1321-1324.
- Wlad Kusnezow,; Anette Jacob,; Alexandra Walijew,; Frank Diehl,;örg D. Hoheisel. Antibody microarrays: An evaluation of production parameters. PROTEOMICS. 2003, 33, 254-264,.
- Sulfhydryl- (SH) and amino-reactive heterobifunctional cross-linking agent: Enzym. Immunoassay, 81 (1981); J. Immunol. Meth., 62, 123 (1983). Applications in immunodiagnostics: Biopolymers, 22, 481 (1983).