Search Thermo Fisher Scientific
項目搜尋
結構搜尋Thermo Scientific Chemicals
N-Fmoc-D-leucine, 98%, Thermo Scientific Chemicals
產品號碼: H29041.03
1 g, Each
化學識別
CAS
114360-54-2
IUPAC Name
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid
Molecular Formula
C21H23NO4
InChI Key
CBPJQFCAFFNICX-TWYLJJHKNA-N
SMILES
CC(C)C[C@@H](NC(=O)OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)C(O)=O
規格
規格表Appearance (Color)
White to pale cream
Melting Point (clear melt)
150.0-157.0?C
Form
Powder
Assay (Aqueous acid-base Titration)
≥97.5 to ≤102.5%
Optical Rotation
24.5 ± 1.0? (C=1 in DMF)
說明
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.
Solubility
Insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
圖表
文件與下載
證書
依批號或部分批號搜尋
常見問答集 (常見問題)
引用資料與參考文獻
Search citations by name, author, journal title or abstract text