Phenanthrene-9-boronic acid, 97%
Phenanthrene-9-boronic acid, 97%
Phenanthrene-9-boronic acid, 97%
Thermo Scientific Chemicals

Phenanthrene-9-boronic acid, 97%

CAS: 68572-87-2 | C14H11BO2 | 222.05 g/mol
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Quantity:
1 g
5 g
產品號碼 H52546.06
亦稱為 H52546-06
價格 (TWD)
-
Quantity:
5 g
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化學識別
CAS68572-87-2
規格Specification Sheet規格表
Assay (HPLC)96.0% min
Phenanthrene-9-boronic acid as a reactant is involved in the synthesis of large polycyclic aromatic hydrocarbons (PAHs) and electron rich benzo[g,h,i]perylenes. It is also used for preparation of FLAP protein inhibitors as anti-inflammatory agents and aminoisoquinolinones as PARP-2 selective inhibitors. As a reactant it is involved in homocoupling reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenanthrene-9-boronic acid as a reactant is involved in the synthesis of large polycyclic aromatic hydrocarbons (PAHs) and electron rich benzo[g,h,i]perylenes. It is also used for preparation of FLAP protein inhibitors as anti-inflammatory agents and aminoisoquinolinones as PARP-2 selective inhibitors. As a reactant it is involved in homocoupling reactions.

Solubility
Soluble in DMSO.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Tse-An Chen; Rai-Shung Liu. Synthesis of large polycyclic aromatic hydrocarbons from bis(biaryl)acetylenes: large planar PAHs with low π-sextets. Organic Letters. 2011, 13,(17), 4644-4647. 
  2. Rosa De Simone; Maria Giovanna Chini; Ines Bruno; Raffaele Riccio; Daniela Mueller; Oliver Werz; Giuseppe Bifulco. Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents. Journal of medicinal and pharmaceutical chemistry. 2011, 54,(6), 1565-1575.