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Thermo Scientific Chemicals
2-Chloro-4-fluoro-5-nitrotoluene, 97%, Thermo Scientific Chemicals
| 產品號碼 | Quantity |
|---|---|
| H63244.06 亦稱為 H63244-06 | 5 g |
化學識別
CAS112108-73-3
IUPAC Name1-chloro-5-fluoro-2-methyl-4-nitrobenzene
Molecular FormulaC7H5ClFNO2
InChI KeyYXVJHZWHPLOEAP-UHFFFAOYSA-N
SMILESCC1=CC(=C(F)C=C1Cl)[N+]([O-])=O
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規格
規格表
規格表Assay (HPLC)>96.0%
2-Chloro-4-fluoro-5-nitrotoluene, is used as a pharmaceutical intermediate. It is also used as Ceritinib intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Chloro-4-fluoro-5-nitrotoluene, is used as a pharmaceutical intermediate. It is also used as Ceritinib intermediate.
Solubility
Slightly soluble in water.
Notes
Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.
2-Chloro-4-fluoro-5-nitrotoluene, is used as a pharmaceutical intermediate. It is also used as Ceritinib intermediate.
Solubility
Slightly soluble in water.
Notes
Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.
RUO – Research Use Only
TH Marsilje.; W Pei.; B Chen.; W Lu.; T Uno. Synthesis, Structure-Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials. J. Med. Chem..201356 (14), 5675-5690.