Activated phenethylamine used in the perfluorooctanesulfonic acid catalyzed Pictet-Spengler reaction. Also used in a synthesis of 1,3-oxazepines via palladium-catalyzed intramolecular coupling.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Activated phenethylamine used in the perfluorooctanesulfonic acid catalyzed Pictet-Spengler reaction. Also used in a synthesis of 1,3-oxazepines via palladium-catalyzed intramolecular coupling.
Solubility
Insoluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- G P Miller; I H Hanna; Y Nishimura; F P Guengerich. Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis. J. Comb. Chem. 2001 40(47), 14215-14223.
- P T Wong; W L Teo; T Lee. A microdialysis study on striatal dopamine, 5-HT and metabolites in conscious rats after various treatments: evidence for extravesicular release of dopamine. Neuroreport. 1993 5(1), 53-56.