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Thermo Scientific Chemicals
Sodium orthovanadate, 100mM aq. soln.
CAS: 13721-39-6 | Na3O4V | 183.907 g/mol
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規格
CAS13721-39-6
ChEBICHEBI:35607
Chemical Name or MaterialSodium orthovanadate
ColorColorless
Concentration or Composition (by Analyte or Components)100mM aq. soln.
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Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.
Solubility
It is soluble in water (50 mg/ml, )
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away fom strong oxidizing agents.
Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.
Solubility
It is soluble in water (50 mg/ml, )
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away fom strong oxidizing agents.
RUO – Research Use Only
General References:
- Ai et al. Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms. World J.Gastroenterol. 2004, 15,(24), 3612-5.
- Matsumoto et al. Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 2006, 318,(3), 982-91.