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Leupeptin hemisulfate
產品號碼: J61188.MB
25 mg, Each
化學識別
CAS
103476-89-7
IUPAC Name
[amino({[(4S)-4-[(2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-4-methylpentanamido]-5-oxopentyl]amino})methylidene]azanium
Molecular Formula
C20H39N6O4
InChI Key
GDBQQVLCIARPGH-ULQDDVLXSA-O
SMILES
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=[NH2+])C=O
規格
規格表Form
Powder
Assay (HPLC)
? 96.5%
Assay (special)
Peptide content: ? 85.0%
Appearance (Color)
White
說明
Reversible protease inhibitor, which inhibits cathepsin B, calpain and trypsinPharmaceutical composition containing leupeptin hemisulfate is used as an anti-malarial agent. It is employed in the treatment of noise-induced hearing loss. It also protects the heart from myocardial stunning. Further, it is used to inhibit serine, cysteine proteases, plasmin, trypsin, papain, kallikrein and cathepsin B.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Reversible protease inhibitor, which inhibits cathepsin B, calpain and trypsinPharmaceutical composition containing leupeptin hemisulfate is used as an anti-malarial agent. It is employed in the treatment of noise-induced hearing loss. It also protects the heart from myocardial stunning. Further, it is used to inhibit serine, cysteine proteases, plasmin, trypsin, papain, kallikrein and cathepsin B.
Solubility
Soluble in water, ethanol, dimethyl formamide and acetic acid.
Notes
Store in a cool place. Incompatible with strong acids and strong bases.
Reversible protease inhibitor, which inhibits cathepsin B, calpain and trypsinPharmaceutical composition containing leupeptin hemisulfate is used as an anti-malarial agent. It is employed in the treatment of noise-induced hearing loss. It also protects the heart from myocardial stunning. Further, it is used to inhibit serine, cysteine proteases, plasmin, trypsin, papain, kallikrein and cathepsin B.
Solubility
Soluble in water, ethanol, dimethyl formamide and acetic acid.
Notes
Store in a cool place. Incompatible with strong acids and strong bases.
RUO – Research Use Only
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