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Thermo Scientific Chemicals
Dextromethorphan hydrobromide
CAS: 125-69-9 | C18H26BrNO | 352.316 g/mol
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化學識別
CAS125-69-9
IUPAC Namehydrogen (1S,9S,10S)-4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0¹,¹⁰.0²,⁷]heptadeca-2,4,6-triene bromide
Molecular FormulaC18H26BrNO
InChI KeyMISZALMBODQYFT-URVXVIKDSA-N
SMILES[H+].[Br-].COC1=CC=C2C[C@H]3[C@H]4CCCC[C@@]4(CCN3C)C2=C1
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規格
規格表
規格表FormCrystalline powder
Assay from Supplier's CofA≥98% (HPLC)
Appearance (Color)White
Optical Rotation+27? to +30? (c = 1.5 in water)
pH5.2-6.5
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It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well. It is used as a pharmaceutical raw material.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well. It is used as a pharmaceutical raw material.
Solubility
Soluble in water (40 mM), and alcohol (1:10).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat pain and a variety of other disturbances as well. It is used as a pharmaceutical raw material.
Solubility
Soluble in water (40 mM), and alcohol (1:10).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- G Ramachander.; FD Williams. Determination of dextrorphan in plasma and evaluation of bioavailability of dextromethorphan hydrobromide in humans. Journal of Pharmaceutical Sciences. 1977, 66, (7), 1047-1048.
- PM Fleming. Dependence on dextromethorphan hydrobromide. BMJ. 1986, 293, (6), 597-599.