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Thermo Scientific Chemicals
Minoxidil
Minoxidil, CAS # 38304-91-5, is a comopund with vasodilating effects that works by opening adenosine triphosphate (ATP)-sensitive potassium channels. | CAS: 38304-91-5 | C9H15N5O | 209.253 g/mol
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化學識別
CAS38304-91-5
IUPAC Name6-amino-2-imino-4-(piperidin-1-yl)-1,2-dihydropyrimidin-1-ol
Molecular FormulaC9H15N5O
InChI KeyZIMGGGWCDYVHOY-UHFFFAOYSA-N
SMILESNC1=CC(=NC(=N)N1O)N1CCCCC1
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規格
規格表
規格表Loss on Drying0.5% max.
Assay (unspecified)98.0% min.
Trace Metals20ppm max.
Residue on ignition0.5% max.
Minoxidil is used as antihypertensive, antialopecia agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Minoxidil is a piperidine that acts as a vasodilator when converted into its active metabolite, minoxidil sulphate
- Minoxidil opens adenosine triphosphate (ATP)-sensitive potassium channels in the plasma membrane and relaxes smooth muscle in arteriole walls. Relaxation of smooth muscle within the arterioles leads to decreased resistance and lower blood pressure
RUO – Research Use Only
General References:
- Proctor PH. Endothelium-derived relaxing factor and minoxidil: active mechanisms in hair growth. Arch Dermatol. 1989 Aug;125(8):1146. PMID: 2757417.
- Nagai N, Iwai Y, Sakamoto A, Otake H, Oaku Y, Abe A, Nagahama T. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice. Int J Nanomedicine. 2019 Oct 1;14:7921-7931. doi: 10.2147/IJN.S225496. PMID: 31632009; PMCID: PMC6778480.