Retinol, 95%, synthetic

Name: Retinol, 95%, synthetic
SKU: J62079.MC

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells. | CAS: 68-26-8 | C20H30O | 286.46 g/mol

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產品號碼 J62079.MC

亦稱為 J62079-MC

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化學識別

CAS68-26-8

IUPAC Name(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

Molecular FormulaC20H30O

InChI KeyFPIPGXGPPPQFEQ-OVSJKPMPSA-N

SMILESC\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C

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規格

規格表

Appearance (Color)Yellow to orange

FormPowder

Assay (special)≥94%

Melting Point60 to 65°C

Proton NMRConforms to structure

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient
• All-trans-retinol is involved in hormonal signaling via the retinoid receptors
• It is an important regulator of cell division and apoptosis
• Deficiency can lead to vision, bone, immune, and skin disorders

Applications
• Suitable for research on cell differentiation, embryonic development, immunology and more
• Laboratory grade quality, for research use only

RUO – Research Use Only

General References:

Stephensen, C.B.; Lietz, G. Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2. Br J Nutr. 2021, 126(11), 1663-1672.
He, J.; Gu, Y.; Zhang, S. Vitamin A and Breast Cancer Survival: A Systematic Review and Meta-analysis. Clin Breast Cancer. 2018, 18(6), e1389-e1400.