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Thermo Scientific Chemicals
N-Acetyl-Ser-Asp-Lys-Pro
| 產品號碼 | Quantity |
|---|---|
| J66430.LB0 亦稱為 J66430-#0 | 5 mg |
化學識別
CAS127103-11-1
IUPAC Name1-{6-amino-2-[3-carboxy-2-(2-acetamido-3-hydroxypropanamido)propanamido]hexanoyl}pyrrolidine-2-carboxylic acid
Molecular FormulaC20H33N5O9
InChI KeyHJDRXEQUFWLOGJ-UHFFFAOYNA-N
SMILESCC(=O)NC(CO)C(=O)NC(CC(O)=O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(O)=O
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規格
規格表
規格表Appearance (Color)White
Purity≥94.0%
Molecular WeightConsistent (Theoretical: 487.5)
FormLyophilized Powder
N-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin converting enzyme, which is responsible for its degradation in vivo.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin
N-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin
RUO – Research Use Only
General References:
- C S Anthony; G Masuyer; E D Sturrock; K R Acharya. Structure based drug design of angiotensin-I converting enzyme inhibitors. Current Medicinal Chemistry.2012, 19, (6), 845-855.
- A Rousseau-Plasse; J Wdzieczak-Bakala; M Lenfant; E Ezan, R Genet; S Robinson; T Briscoe; J Melville; A Riches. Lisinopril, an angiotensin I-converting enzyme inhibitor, prevents entry of murine hematopoietic stem cells into the cell cycle after irradiation in vivo. Experimental Hematology.1998, 26, (11), 1074-1079.
內容物與存放
Store at -20°C