Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
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Applications
Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.
Solubility
Soluble in water. (100 g/L) at 20°C.
Notes
Hygroscopic. Store at 4°C. Incomaptible with Strong acids and oxidizing agents.
RUO – Research Use Only
General References:
- Muriel E. Farquharson and R. G. Johnston. Antagonism Of The Effects Of Tremorine By Tropine Derivatives.British Journal of Pharmacology and Chemotherapy.1959, 14 559-566.
- Edward. Leete. The Stereospecific Incorporation of Ornithine into the Tropine Moiety of Hyoscyamine.J. Am. Chem. Soc.1962, 84 (1), 55-57.