Search
項目搜尋
結構搜尋
Thermo Scientific Chemicals
1-Phenyl-1-trimethylsiloxyethylene, 95%
CAS: 13735-81-4 | C11H16OSi | 192.333 g/mol
Have Questions?
變更視圖
化學識別
CAS13735-81-4
IUPAC Nametrimethyl[(1-phenylethenyl)oxy]silane
Molecular FormulaC11H16OSi
InChI KeyAFFPCIMDERUIST-UHFFFAOYSA-N
SMILESC[Si](C)(C)OC(=C)C1=CC=CC=C1
檢視更多
規格表1-Phenyl-1-trimethylsiloxyethylene has been used in the synthesis of β-amino ketones in water via Mannich-type reaction and cis-2,6-disubstituted dihydropyrans via three-component, one-pot cascade reaction. It is also used as chemical additives and intermediates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Phenyl-1-trimethylsiloxyethylene has been used in the synthesis of β-amino ketones in water via Mannich-type reaction and cis-2,6-disubstituted dihydropyrans via three-component, one-pot cascade reaction. It is also used as chemical additives and intermediates.
Solubility
Reacts with water.
Notes
Store at 4°C. Moisture Sensitive. Store under inert gas. Incompatible materials are Oxidizing agents.
1-Phenyl-1-trimethylsiloxyethylene has been used in the synthesis of β-amino ketones in water via Mannich-type reaction and cis-2,6-disubstituted dihydropyrans via three-component, one-pot cascade reaction. It is also used as chemical additives and intermediates.
Solubility
Reacts with water.
Notes
Store at 4°C. Moisture Sensitive. Store under inert gas. Incompatible materials are Oxidizing agents.
RUO – Research Use Only
General References:
- Teck-Peng Loh; Lin-Li Wei. Novel one-pot Mannich-type reaction in water: Indium trichloride-catalyzed condensation of aldehydes, amines and silyl enol ethers for the synthesis of β-amino ketones and esters.Tetrahedron Letters. 1998,33 323-326.
- Yanlong Gu; Rodolphe De Sousa; Gilles Frapper; Christian Bachmann; Joël Barraulta and François Jérôme. Catalyst-free aqueous multicomponent domino reactions from formaldehyde and 1,3-dicarbonyl derivatives.Green Chem. 2009,11 1968-1972.
- The TiCl4 promoted crossed aldol condensation with acetone illustrates the reaction of silyl enol ethers with aldehydes and ketones: Org. Synth. Coll., 8, 323 (1993). For a further example and reaction scheme, see 1-(Trimethyl siloxy) cyclohexene, A16099. For an alternative catalyst for this type of reaction, see Tetra-n-butyl ammonium fluoride, A10588.
- ɑ-Arylation with diazonium fluoroborates to give ɑ-arylacetophenones (deoxybenzoins) occurs in pyridine, and also in other solvents in the presence of a Pd catalyst: J. Chem. Soc. Perkin 1, 283 (1994).
- For a review of the synthetic applications of silyl enol ethers, see: Synthesis, 91 (1977).