(S)-(+)-Prolinol, 98%
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(S)-(+)-Prolinol, 98%
(S)-(+)-Prolinol, 98%
(S)-(+)-Prolinol, 98%
Thermo Scientific Chemicals

(S)-(+)-Prolinol, 98%

CAS: 23356-96-9 | C5H11NO | 101.149 g/mol
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產品號碼 L09779.06
亦稱為 L09779-06
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5 g
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化學識別
CAS23356-96-9
IUPAC Name(pyrrolidin-2-yl)methanol
Molecular FormulaC5H11NO
InChI KeyHVVNJUAVDAZWCB-UHFFFAOYNA-N
SMILESOCC1CCCN1
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規格Specification Sheet規格表
Appearance (Color)Clear colorless to yellow to green or blue
FormLiquid or viscous liquid
Water Content (Karl Fischer Titration)≤1%
Refractive Index1.4830-1.4870 @ 20?C
Assay (GC)≥97.5%
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It is an active pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is an active pharmaceutical intermediate.

Solubility
Fully miscible in water. Soluble in chloroform.

Notes
Store at room temperature. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Shinichi Itsuno.; Koichi Ito.; Akira Hirao.; Seiichi Nakahama. Asymmetric synthesis using chirally modified borohydrides. Part 2. Enantioselective reduction of ketones with polymeric (S)-prolinol-borane reagent.J. Chem. Soc., Perkin Trans. 1. 1984, 2887-2893 .
  2. David Alker.; Kevin J. Doyle.; Laurence M. Harwood.; Andrew McGregor. The direct synthesis of the cyclic sulphamidate of (S)-prolinol: SimultaneousN-protection and activation towards nucleophilic displacement of oxygen.Tetrahedron: Asymmetry. 1990, 1 (12),877-880 .