Benzyl (R)-(-)-glycidyl ether, 98+%
Benzyl (R)-(-)-glycidyl ether, 98+%
Benzyl (R)-(-)-glycidyl ether, 98+%
Benzyl (R)-(-)-glycidyl ether, 98+%
Thermo Scientific Chemicals

Benzyl (R)-(-)-glycidyl ether, 98+%

CAS: 14618-80-5 | C10H12O2 | 164.204 g/mol
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5 g
產品號碼 L13980.03
亦稱為 L13980-03
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化學識別
CAS14618-80-5
IUPAC Name(2R)-2-[(benzyloxy)methyl]oxirane
Molecular FormulaC10H12O2
InChI KeyQNYBOILAKBSWFG-JTQLQIEISA-N
SMILESC(OCC1=CC=CC=C1)[C@H]1CO1
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規格Specification Sheet規格表
Appearance (Color)Clear colorless
Refractive Index1.5160-1.5200 @ 20?C
FormLiquid
Optical Rotation-5.2 ± 0.2? (c=5 in toluene)
Assay (GC)≥98.0%
Benzyl (R)-(-)-glycidyl ether is used in the preparation of the lactone fragment of compactin and mevinolin. Chiron in the preparation of syn-1,3-polyols, dideoxynucleosides, and a spiroacetal cyanohydrin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl (R)-(-)-glycidyl ether is used in the preparation of the lactone fragment of compactin and mevinolin. Chiron in the preparation of syn-1,3-polyols, dideoxynucleosides, and a spiroacetal cyanohydrin.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. E Abushanab; M S Sarma. 1',2'-seco-dideoxynucleosides as potential anti-HIV agents. Journal of Medicinal Chemistry. 1989, 32, (1), 76-79.
  2. Fatih M. Uckun; Chen Mao, Alexei O. Vassilev; He Huang; Shyi-Tai Jan. Structure-based design of a novel synthetic spiroketal pyran as a pharmacophore for the marine natural product spongistatin 1. Bioorganic & Medicinal Chemistry Letters. 2000, 10, (6), 541-545.