PIP Strips™ membranes are designed for the identification of proteins possessing phosphoinositide recognition domains and for analysis of their lipid-binding specificities. PIP Strips™ membranes facilitate the analysis of phosphoinositide protein interactions by protein-lipid overlay assays. Proteins may be detected using standard western blot procedures in conjunction with high-performance alkaline phosphatase- and horseradish peroxidase (HRP)-mediated signal generation systems.