Peroxisome Proliferator-activated Receptor Gamma

  • Product Reviews (0)
  • Citations (1)

General Description

Research indicates that genetic variations are key for understanding the genetic basis of complex traits and diseases. Variants can influence phenotypes, the susceptibility of an individual to disease, drug response and human genome evolution. Many SNPs have been associated with common disorders such as diabetes, obesity, and cardiovascular diseases. Further research into identifying the risk factors and understanding the biology of risk variants would enable a more complete view of these conditions and lead to improved disease treatment and prevention.


Studies show that the Pro12Ala polymorphism in exon 2 of PPARG reduces transcriptional activity of PPARγ2 and may be associated with increased insulin sensitivity and protection from Type 2 Diabetes.

Target Disease/Application

Peroxisome Proliferator-activated Receptor Gamma

Assay ID Clinical Name Gene Symbol Gene Name dbSNP ID  
C___1129864_10 PPARG P12A PPARG Peroxisome Proliferator-activated Receptor Gamma rs1801282


General Specifications

# of assays: 1
Technology: TaqMan® Assays
Scale: Available in multiple scales
Intended Use: Research Use Only

Contents and Storage

-20° C


Citations & References (1)

  • Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone.

Florez JC,
J Clin Endocrinol Metab. (2007) 92:1502-9.