The panel of assays in the TaqMan® Array 96-well Human Hypoxia Plate targets genes in the HIF (hypoxia inducible factor) family. On the panel are the genes VHL, Cul2, and RBX1 (Ring-Box 1) that complex with additional genes for a role in the ubiquitylation of HIF1A. Other hypoxia response related genes fall in to the following target classes: Transcription Factors, Immune and Stress Response, Signal Transduction, Apoptosis, Oxidoreductases, Proteases, and Protein metabolism.

ADM, ANGPTL4, ARNT, ARNT2, ATP1B1, BHLHB2, CASP1, CREBBP, CUL2, DDIT4, DDIT4L, EDN1, EGLN1, EGLN2, EGLN3, EP300, EPAS1, EPO, FRAP1, HIF1A, HIF1AN, HIF3A, HIG2, HMOX1, HYOU1, IGFBP1, ING4, MB, MT3, NOS1, NOS2A, NOS3, NOTCH1, PIK3CA, PRKAA1, PRKAA2, PTEN, RBX1, SLC2A8, SOD3, TGFBR2, TP53, VEGFA, VHL