Panel Description

The panel of assays in the TaqMan® Array 96-well Human TGFB Pathway Plate targets genes encoding members of the TGF-Beta superfamily of ligands: 1) TGFB family (TGF- B1, B2, B3); 2) Bone morphogenetic proteins (BMPs); 3) Growth and differentiation factors (GDFs); and 4) Others that include Anti-m®llerian hormone (AMH), Activin A&B/Inihibin A&B, and Nodal. The TGF Beta receptors in the panel include Activin Type 1 and Type II Receptors, BMPRs, and TGFBR 1, 2 and 3. Members of ...
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Targets

ACVR1, ACVR1B, ACVR1C, ACVR2A, ACVR2B, AMH, AMHR2, BMP10, BMP15, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7, BMPER, BMPR1B, BMPR2, CDH1, CHRD, CREBBP, CUL1, DCN, E2F4, E2F5, EP300, FMOD, FNTA, FST, GDF10, GDF11, GDF15, GDF2, GDF3, GDF5, GDF7, GDF9, HIPK2, IFNG, IL17F, IL6, INHA, INHBA, INHBB, INHBC, INHBE, LEFTY1, LEFTY2, LTBP...
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Controls

18S, GAPDH, GUSB, HPRT1

Pathway Information

Cell proliferation in somatic tissues, specification of cell fate during embryogenesis, differentiation and cell death are controlled by a multitude of cell-cell signals. The TGF-Beta (Transforming Growth Factor) superfamily of secreted proteins is one of ...
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Supported Applied Biosystems Instruments

7500 Fast Real-Time PCR System , StepOnePlus™ System , ViiA™ 7 System , 7900HT Real-Time PCR System , QuantStudio™ 12K Flex System , QuantStudio™ 7 Flex System , QuantStudio™ 6 Flex System , QuantStudio™ 5 System , QuantStudio™ 3 System

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