Product Details

SNP ID

rs150067777

Assay Type

Functionally Tested

NCBI dbSNP Submissions

NA

Location

Chr.15:79845222 on Build GRCh38

Set Membership

Context Sequence [VIC/FAM]

TAGTAATCCAGATTTAAGCTGTTGA[C/T]GAGTCTTCGTAAAGGACTTCATCTA

Phenotype

MIM: 604197

Polymorphism

C/T, Transition Substitution

Allele Nomenclature

Literature Links

MTHFS PubMed Links

Additional Information

For this assay, SNP(s) [rs8923] are located under a probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

Gene Details

Gene

MTHFS

Gene Name

5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)

Transcript Accession	SNP Location	SNP Type	Codon Change	Amino Acid Change	Protein ID
NM_001199758.1	607	Silent Mutation	TCA,TCG	S143S	NP_001186687.1
NM_006441.3	607	Silent Mutation	TCA,TCG	S200S	NP_006432.1

Gene

ST20-MTHFS

Gene Name

ST20-MTHFS readthrough

Transcript Accession	SNP Location	SNP Type	Codon Change	Amino Acid Change	Protein ID
NM_001199760.1	607	Silent Mutation	TCA,TCG	S176S	NP_001186689.1

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