The panel of assays in the TaqMan® Array 96-well Human WNT Pathway Plate targets genes from the WNT family of cell-cell signaling proteins. Additionally, modifiers of WNT signaling, including members of the Frizzled GPCR family, Disheveled family, and the Secreted frizzled related family, are included. Other WNT related genes involved in regulation of WNT genes and their targets, signal transduction, embryogenesis, and cancer are also in the panel.
APC, AXIN1, AXIN2, BTRC, CBY1, CSNK1A1, CSNK1D, CSNK1G1, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSNK2B, CTNNB1, CTNNBIP1, CXXC4, DACT1, DKK1, DKK2, DKK3, DKK4, DVL1, DVL2, DVL3, EP300, FBXW11, FGF4, FOXN1, FRAT1, FRAT2, FRZB, FZD1, FZD10, FZD2, FZD3, FZD4, FZD6, FZD7, FZD8, FZD9, GSK3A, GSK3B, KREMEN1, KREMEN2, LEF1, LRP5...
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18S, GAPDH, GUSB, HPRT1
The WNT signaling pathway is complex network of proteins that have roles in embryogenesis, cancer, as well as normal physiological processes in adult animals. The WNT pathway involves a large number of proteins that, regulate the production of WNT signali ...
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