Panel Description

The panel of assays in the TaqMan® Array 96-well Human WNT Pathway Plate targets genes from the WNT family of cell-cell signaling proteins. Additionally, modifiers of WNT signaling, including members of the Frizzled GPCR family, Disheveled family, and the Secreted frizzled related family, are included. Other WNT related genes involved in regulation of WNT genes and their targets, signal transduction, embryogenesis, and cancer are also in the panel.

Targets

APC, AXIN1, AXIN2, BTRC, CBY1, CSNK1A1, CSNK1D, CSNK1G1, CSNK1G2, CSNK1G3, CSNK2A1, CSNK2A2, CSNK2B, CTNNB1, CTNNBIP1, CXXC4, DACT1, DKK1, DKK2, DKK3, DKK4, DVL1, DVL2, DVL3, EP300, FBXW11, FGF4, FOXN1, FRAT1, FRAT2, FRZB, FZD1, FZD10, FZD2, FZD3, FZD4, FZD6, FZD7, FZD8, FZD9, GSK3A, GSK3B, KREMEN1, KREMEN2, LEF1, LRP5...
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Controls

18S, GAPDH, GUSB, HPRT1

Pathway Information

The WNT signaling pathway is complex network of proteins that have roles in embryogenesis, cancer, as well as normal physiological processes in adult animals. The WNT pathway involves a large number of proteins that, regulate the production of WNT signali ...
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Supported Applied Biosystems Instruments

7500 Real-Time PCR System , 7300 Real-Time PCR System , ViiA™ 7 System , 7900HT Real-Time PCR System , QuantStudio™ 12K Flex System , QuantStudio™ 7 Flex System , QuantStudio™ 6 Flex System , QuantStudio™ 5 System , QuantStudio™ 3 System

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